Blood groups and serum cholesterol among 10,000 adult males

J. H. Medalie; C. Levene; C. Papier; U. Goldbourt; F. Dreyfuss; D. Oron; H. Neufeld; E. Riss

doi:10.1016/0021-9150(71)90051-7

Blood groups and serum cholesterol among 10,000 adult males

J. H. Medalie^*, C. Levene, C. Papier, U. Goldbourt, F. Dreyfuss, D. Oron, H. Neufeld, E. Riss

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

An analysis of blood groups and cholesterol has been made as part of a longterm prospective investigation of ischemic heart disease among 10,000 Israeli males, aged 40 and over. The total mean serum cholesterol level for men of blood group A1 was found to be significantly higher than the mean for the combined ABO groups, although this did not hold for every individual country of origin. Among the Rh, MN, Kell, Duffy, and Kidd blood groups, Kell was the only one which showed a significant association with mean serum cholesterol. Men with both A1 and Kell+ exhibited a higher mean cholesterol level than either group separately. The question is raised whether the significant statistical associations in this study population have biological implications.

Original language	English
Pages (from-to)	219-229
Number of pages	11
Journal	Atherosclerosis
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/0021-9150(71)90051-7
State	Published - 1971
Externally published	Yes

Keywords

Blood groups A1 and Kell+
Epidemiology
Serum cholesterol

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10.1016/0021-9150(71)90051-7

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title = "Blood groups and serum cholesterol among 10,000 adult males",

abstract = "An analysis of blood groups and cholesterol has been made as part of a longterm prospective investigation of ischemic heart disease among 10,000 Israeli males, aged 40 and over. The total mean serum cholesterol level for men of blood group A1 was found to be significantly higher than the mean for the combined ABO groups, although this did not hold for every individual country of origin. Among the Rh, MN, Kell, Duffy, and Kidd blood groups, Kell was the only one which showed a significant association with mean serum cholesterol. Men with both A1 and Kell+ exhibited a higher mean cholesterol level than either group separately. The question is raised whether the significant statistical associations in this study population have biological implications.",

keywords = "Blood groups A1 and Kell+, Epidemiology, Serum cholesterol",

author = "Medalie, {J. H.} and C. Levene and C. Papier and U. Goldbourt and F. Dreyfuss and D. Oron and H. Neufeld and E. Riss",

note = "Funding Information: This study is a collaborative project with the National Heart Institute, Bethesda, Md. (U.S.A.), and is supported by P.L. 480 Counterpart Funds, Research Agreement No. 375106. Requests for reprints should be addressed to: J.H.M., Department of Family Medicine, Bldg. 130, Tel Hashomer Hospital, Ramat Gan (Israel).",

year = "1971",

doi = "10.1016/0021-9150(71)90051-7",

language = "אנגלית",

volume = "14",

pages = "219--229",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Blood groups and serum cholesterol among 10,000 adult males

AU - Medalie, J. H.

AU - Levene, C.

AU - Papier, C.

AU - Goldbourt, U.

AU - Dreyfuss, F.

AU - Oron, D.

AU - Neufeld, H.

AU - Riss, E.

N1 - Funding Information: This study is a collaborative project with the National Heart Institute, Bethesda, Md. (U.S.A.), and is supported by P.L. 480 Counterpart Funds, Research Agreement No. 375106. Requests for reprints should be addressed to: J.H.M., Department of Family Medicine, Bldg. 130, Tel Hashomer Hospital, Ramat Gan (Israel).

PY - 1971

Y1 - 1971

N2 - An analysis of blood groups and cholesterol has been made as part of a longterm prospective investigation of ischemic heart disease among 10,000 Israeli males, aged 40 and over. The total mean serum cholesterol level for men of blood group A1 was found to be significantly higher than the mean for the combined ABO groups, although this did not hold for every individual country of origin. Among the Rh, MN, Kell, Duffy, and Kidd blood groups, Kell was the only one which showed a significant association with mean serum cholesterol. Men with both A1 and Kell+ exhibited a higher mean cholesterol level than either group separately. The question is raised whether the significant statistical associations in this study population have biological implications.

AB - An analysis of blood groups and cholesterol has been made as part of a longterm prospective investigation of ischemic heart disease among 10,000 Israeli males, aged 40 and over. The total mean serum cholesterol level for men of blood group A1 was found to be significantly higher than the mean for the combined ABO groups, although this did not hold for every individual country of origin. Among the Rh, MN, Kell, Duffy, and Kidd blood groups, Kell was the only one which showed a significant association with mean serum cholesterol. Men with both A1 and Kell+ exhibited a higher mean cholesterol level than either group separately. The question is raised whether the significant statistical associations in this study population have biological implications.

KW - Blood groups A1 and Kell+

KW - Epidemiology

KW - Serum cholesterol

UR - http://www.scopus.com/inward/record.url?scp=0015118219&partnerID=8YFLogxK

U2 - 10.1016/0021-9150(71)90051-7

DO - 10.1016/0021-9150(71)90051-7

M3 - מאמר

AN - SCOPUS:0015118219

VL - 14

SP - 219

EP - 229

JO - Atherosclerosis

JF - Atherosclerosis

SN - 0021-9150

IS - 2

ER -

Blood groups and serum cholesterol among 10,000 adult males

Abstract

Keywords

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