An analysis of blood groups and cholesterol has been made as part of a longterm prospective investigation of ischemic heart disease among 10,000 Israeli males, aged 40 and over. The total mean serum cholesterol level for men of blood group A1 was found to be significantly higher than the mean for the combined ABO groups, although this did not hold for every individual country of origin. Among the Rh, MN, Kell, Duffy, and Kidd blood groups, Kell was the only one which showed a significant association with mean serum cholesterol. Men with both A1 and Kell+ exhibited a higher mean cholesterol level than either group separately. The question is raised whether the significant statistical associations in this study population have biological implications.
- Blood groups A1 and Kell+
- Serum cholesterol