Reparation biventriculaire chez les nouveau-nes ducto-dependants avec hypoplasie relative des cavites gauches

Translated title of the contribution: Biventricular repair of small left ventricle in ducto-dependent neonates

A. Serraf, J. D. Piot, F. Lacour-Gayet, A. Touchot, J. Bruniaux, E. Belli, C. Planché

Research output: Contribution to journalArticlepeer-review

Abstract

Background. Whether to perform uni or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal left ventricle and multi level left ventricle obstructions (hypoplastic left heart syndrome class III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. Hypothesis. Increased afterload and multi level left ventricle obstruction is constant. We assumed that restoration of normal loading conditions by relief of left ventricle obstructions promotes its growth, provided that part of the cardiac output was pre operatively supported by the left ventricle, whatever the echocardiographic indices. Methods. Twenty one ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multi level left ventricle obstruction. Pre operative echocardiographic assessment showed: mean end diastolic left ventricular volume of 13.3 ± 3.5 mL/m2 and mean Rhodes score of -1.43 ± 0.9. Surgery consisted in relief of left ventricle outflow tract obstruction by coarctation repair in 21 associated to atrial septal defect closure in 2, aortic commissurotomy in I and ascending aorta enlargement in 1. Results. There were 3 early and 3 late deaths. There was no predictive risk factor for failure. Growth of the left heart was demonstrated in most patients. At hospital discharge the end diastolic left ventricular volume was 19.4 ± 3.12 mL/m2 (p = 0.0001) and the Rhodes score was -0.38 ± 1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were: 68.5% and 40.75%, respectively. Conclusion. Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal left ventricle provided that all anatomical causes of left ventricle obstruction can be relieved. Secondary growth of the left heart then occurs, however the reoperation rate is not low.

Translated title of the contributionBiventricular repair of small left ventricle in ducto-dependent neonates
Original languageFrench
Pages (from-to)597-605
Number of pages9
JournalArchives des Maladies du Coeur et des Vaisseaux
Volume92
Issue number5
StatePublished - May 1999

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