TY - JOUR
T1 - Biventricular repair approach in ducto-dependent neonates with hypoplastic but morphologically normal left ventricle
AU - Serraf, Alain
AU - Piot, Jean Dominique
AU - Bonnet, Nicolas
AU - Lacour-Gayet, François
AU - Touchot, Anita
AU - Bruniaux, Jacqueline
AU - Belli, Emré
AU - Galletti, Lorenzo
AU - Planché, Claude
PY - 1999/3/1
Y1 - 1999/3/1
N2 - OBJECTIVES: Increased afterload and multilevel LV obstruction is constant. We assumed that restoration of normal loading conditions by relief of LV obstructions promotes its growth, provided that part of the cardiac output was preoperatively supported by the LV, whatever the echocardiographic indexes. BACKGROUND: Whether to perform uni- or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal LV (hypoplastic left heart syndrome classes II and III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. METHODS: Twenty ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multilevel LV obstruction. Preoperative echocardiographic assessment showed: mean EDLW of 12.4 ± 3.03 ml/m2 and mean Rhodes score of -1.73 ± 0.8. Surgery consisted in relief of LV outflow tract obstruction by coarctation repair in all associated to aortic commissurotomy in one and ASD closure in 2. RESULTS: There were 3 early and 2 late deaths. Failure of biventricular repair and LV growth was obvious in patients with severe anatomic mitral stenosis. The other demonstrated growth of the left heart. At hospital discharge the EDLW was 19.4 ± 3.12 ml/m2 (p = 0.0001) and the Rhodes score was -0.38 ± 1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were 72.5% and 46%, respectively. CONCLUSIONS: Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal LV provided that all anatomical causes of LV obstruction can be relieved. Secondary growth of the left heart then occurs; however, the reoperation rate is high.
AB - OBJECTIVES: Increased afterload and multilevel LV obstruction is constant. We assumed that restoration of normal loading conditions by relief of LV obstructions promotes its growth, provided that part of the cardiac output was preoperatively supported by the LV, whatever the echocardiographic indexes. BACKGROUND: Whether to perform uni- or biventricular repair in ducto dependent neonates with hypoplastic but morphologically normal LV (hypoplastic left heart syndrome classes II and III) remains unanswered. Echocardiographic criteria have been proposed for surgical decision. METHODS: Twenty ducto dependent neonates presented with this anomaly. All had aortic coarctation associated to multilevel LV obstruction. Preoperative echocardiographic assessment showed: mean EDLW of 12.4 ± 3.03 ml/m2 and mean Rhodes score of -1.73 ± 0.8. Surgery consisted in relief of LV outflow tract obstruction by coarctation repair in all associated to aortic commissurotomy in one and ASD closure in 2. RESULTS: There were 3 early and 2 late deaths. Failure of biventricular repair and LV growth was obvious in patients with severe anatomic mitral stenosis. The other demonstrated growth of the left heart. At hospital discharge the EDLW was 19.4 ± 3.12 ml/m2 (p = 0.0001) and the Rhodes score was -0.38 ± 1.01 (p = 0.0003). Actuarial survival and freedom from reoperation rates at 5 years were 72.5% and 46%, respectively. CONCLUSIONS: Biventricular repair can be proposed to ducto dependent neonates with hypoplastic but morphologically normal LV provided that all anatomical causes of LV obstruction can be relieved. Secondary growth of the left heart then occurs; however, the reoperation rate is high.
UR - http://www.scopus.com/inward/record.url?scp=0033101504&partnerID=8YFLogxK
U2 - 10.1016/S0735-1097(98)00636-6
DO - 10.1016/S0735-1097(98)00636-6
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C2 - 10080488
AN - SCOPUS:0033101504
SN - 0735-1097
VL - 33
SP - 827
EP - 834
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 3
ER -