Bisquaternary pyridinium oximes as allosteric inhibitors of rat brain muscarinic receptors

Keyphrases

• Allosteric Inhibitor 100%
• Brainstem 100%
• Rat Brain 100%
• Muscarinic Receptors 100%
• Pyridinium Oximes 100%
• Muscarinic Antagonists 75%
• Binding Site 50%
• Irreversible Effect 50%
• Dissociation 25%
• Muscarinic Acetylcholine Receptor 25%
• Cortex 25%
• Binding Data 25%
• Binding Capacity 25%
• Cerebral Cortex 25%
• Non-exclusive 25%
• In Vivo Effects 25%
• N-methylation 25%
• Binding Properties 25%
• Receptor Sites 25%
• Interaction Mode 25%
• K(I) 25%
• Benzil 25%
• Kinetic Binding 25%
• Potent Inhibitor 25%
• Tritium 25%
• Equilibrium Binding 25%
• Dimethyl Ether 25%
• Washing out 25%
• Oxime 25%
• Receptor States 25%

Neuroscience

• Muscarinic Acetylcholine Receptor 100%
• Oxime 100%
• Brainstem 80%
• Muscarinic Antagonist 60%
• Eicosanoid Receptor 60%
• In Vivo 40%
• In Vitro 40%
• Binding Site 40%
• Receptor Agonists 20%
• Cerebral Cortex 20%
• Binding Kinetics 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Muscarinic Receptor 100%
• Oxime 100%
• Muscarinic Receptor Blocking Agent 60%
• Receptor 60%
• Binding Site 40%
• Receptor Agonist 20%
• Benzilic Acid 20%
• Tritium 20%
• Dimethyl Ether 20%