Bis(nateglinide) hydronium chloride, and its unique self-assembly into extended polymeric arrays via O - H O, N - H⋯Cl and O - H⋯Cl hydrogen bonds

Limor Tessler, Israel Goldberg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The title compound, bis[(-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D- phenylalanine] hydronium chloride, 2C19H27NO 3·H3O+·Cl-, at 110 K contains four conformationally dissimilar moieties in the asymmetric unit, which are seemingly necessary in order to optimize the supramolecular association. The organic molecule forms O - H⋯O hydrogen-bonded carboxylic acid dimers, which are paired into six-component clusters via N - H⋯Cl hydrogen bonds through the two bridging chloride anions. These combined hexameric aggregates are further interlinked into extended two-dimensional network arrays via the hydronium ions by O - H⋯O and O - H⋯Cl hydrogen bonds. This study represents the first crystallographic report of nateglinide.

Original languageEnglish
Pages (from-to)o738-o740
JournalActa Crystallographica Section C: Crystal Structure Communications
Volume61
Issue number12
DOIs
StatePublished - Dec 2005

Fingerprint

Dive into the research topics of 'Bis(nateglinide) hydronium chloride, and its unique self-assembly into extended polymeric arrays via O - H O, N - H⋯Cl and O - H⋯Cl hydrogen bonds'. Together they form a unique fingerprint.

Cite this