Biosynthesis and accumulation of formic acid in the poison gland of the carpenter ant Camponotus pennsylvanicus

Abraham Hefetz*, Murray S. Blum

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Formic acid synthesis in the poison gland of Camponotus pennsylvanicus is closely related to the C-1 metabolism of the glandular cells. Serine, glycine, and histidine are potential C-1 donors to formic acid by several tetrahydrofolate intermediates. Formic acid is accumulated by its transfer to an insulated reservoir, so that the ant avoids the acid's cytotoxicity. This combination of biochemical and morphological features provides an autodefensive mechanism. Possible factors that regulate the biosynthesis of formic acid in the poison gland apparatus are discussed.

Original languageEnglish
Pages (from-to)454-455
Number of pages2
JournalScience
Volume201
Issue number4354
DOIs
StatePublished - 1978
Externally publishedYes

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