TY - JOUR
T1 - Bioprosthetic Aortic Valve Thrombosis
T2 - Definitions, Clinical Impact, and Management: A State-of-the-Art Review
AU - Chitturi, Kalyan R.
AU - Aladin, Amer I.
AU - Braun, Ryan
AU - Al-Qaraghuli, Abdullah K.
AU - Banerjee, Avantika
AU - Reddy, Pavan
AU - Merdler, Ilan
AU - Chaturvedi, Abhishek
AU - Abusnina, Waiel
AU - Haberman, Dan
AU - Lupu, Lior
AU - Rodriguez-Weisson, Fernando J.
AU - Case, Brian C.
AU - Wermers, Jason P.
AU - Ben-Dor, Itsik
AU - Satler, Lowell F.
AU - Waksman, Ron
AU - Rogers, Toby
N1 - Publisher Copyright:
© 2024 American Heart Association, Inc.
PY - 2024/7/1
Y1 - 2024/7/1
N2 - Bioprosthetic aortic valve thrombosis is frequently detected after transcatheter and surgical aortic valve replacement due to advances in cardiac computed tomography angiography technology and standardized surveillance protocols in low-surgical-risk transcatheter aortic valve replacement trials. However, evidence is limited concerning whether subclinical leaflet thrombosis leads to clinical adverse events or premature structural valve deterioration. Furthermore, there may be net harm in the form of bleeding from aggressive antithrombotic treatment in patients with subclinical leaflet thrombosis. This review will discuss the incidence, mechanisms, diagnosis, and optimal management of bioprosthetic aortic valve thrombosis after transcatheter aortic valve replacement and bioprosthetic surgical aortic valve replacement.
AB - Bioprosthetic aortic valve thrombosis is frequently detected after transcatheter and surgical aortic valve replacement due to advances in cardiac computed tomography angiography technology and standardized surveillance protocols in low-surgical-risk transcatheter aortic valve replacement trials. However, evidence is limited concerning whether subclinical leaflet thrombosis leads to clinical adverse events or premature structural valve deterioration. Furthermore, there may be net harm in the form of bleeding from aggressive antithrombotic treatment in patients with subclinical leaflet thrombosis. This review will discuss the incidence, mechanisms, diagnosis, and optimal management of bioprosthetic aortic valve thrombosis after transcatheter aortic valve replacement and bioprosthetic surgical aortic valve replacement.
KW - anticoagulants
KW - aortic valve
KW - bioprosthesis
KW - computed tomography angiography
KW - echocardiography
KW - thrombosis
KW - transcatheter aortic valve replacement
UR - http://www.scopus.com/inward/record.url?scp=85198395931&partnerID=8YFLogxK
U2 - 10.1161/CIRCINTERVENTIONS.123.014143
DO - 10.1161/CIRCINTERVENTIONS.123.014143
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C2 - 38853766
AN - SCOPUS:85198395931
SN - 1941-7640
VL - 17
SP - e014143
JO - Circulation: Cardiovascular Interventions
JF - Circulation: Cardiovascular Interventions
IS - 7
ER -