BiometryNet: Landmark-based Fetal Biometry Estimation from Standard Ultrasound Planes

Netanell Avisdris*, Leo Joskowicz, Brian Dromey, Anna L. David, Donald M. Peebles, Danail Stoyanov, Dafna Ben Bashat, Sophia Bano

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Fetal growth assessment from ultrasound is based on a few biometric measurements that are performed manually and assessed relative to the expected gestational age. Reliable biometry estimation depends on the precise detection of landmarks in standard ultrasound planes. Manual annotation can be time-consuming and operator dependent task, and may results in high measurements variability. Existing methods for automatic fetal biometry rely on initial automatic fetal structure segmentation followed by geometric landmark detection. However, segmentation annotations are time-consuming and may be inaccurate, and landmark detection requires developing measurement-specific geometric methods. This paper describes BiometryNet, an end-to-end landmark regression framework for fetal biometry estimation that overcomes these limitations. It includes a novel Dynamic Orientation Determination (DOD) method for enforcing measurement-specific orientation consistency during network training. DOD reduces variabilities in network training, increases landmark localization accuracy, thus yields accurate and robust biometric measurements. To validate our method, we assembled a dataset of 3,398 ultrasound images from 1,829 subjects acquired in three clinical sites with seven different ultrasound devices. Comparison and cross-validation of three different biometric measurements on two independent datasets shows that BiometryNet is robust and yields accurate measurements whose errors are lower than the clinically permissible errors, outperforming other existing automated biometry estimation methods. Code is available at https://github.com/netanellavisdris/fetalbiometry.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2022 - 25th International Conference, Proceedings
EditorsLinwei Wang, Qi Dou, P. Thomas Fletcher, Stefanie Speidel, Shuo Li
PublisherSpringer Science and Business Media Deutschland GmbH
Pages279-289
Number of pages11
ISBN (Print)9783031164392
DOIs
StatePublished - 2022
Event25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022 - Singapore, Singapore
Duration: 18 Sep 202222 Sep 2022

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume13434 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022
Country/TerritorySingapore
CitySingapore
Period18/09/2222/09/22

Funding

FundersFunder number
Israel Innovation Authority
Engineering and Physical Sciences Research CouncilEP/P012841/1, EP/P027938/1, EP/R004080/1
Royal Academy of Engineering
Horizon 202072126, 63418, 863146
Wellcome / EPSRC Centre for Interventional and Surgical Sciences203145/Z/16/Z

    Keywords

    • Anatomical landmarks’ localisation
    • Computer-assisted diagnosis
    • Fetal biometry estimation
    • Fetal ultrasound

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