Bioinspired design of nanocages by self-assembling triskelion peptide elements

Surajit Ghosh, Meital Reches, Ehud Gazit, Sandeep Verma

Research output: Contribution to journalArticlepeer-review

Abstract

Winning the three-legged race: Rapid self-organization of a tripodal aromatic dipeptide conjugate on a tris(2-amino-ethyl)amine scaffold leads to a vesicular morphology (upper image). The structures can trap a fluorescent dye (lower image) and release it upon acidification, suggesting the use of such stimuli-responsive materials as potential delivery vehicles. (Figure Presented).

Original languageEnglish
Pages (from-to)2002-2004
Number of pages3
JournalAngewandte Chemie - International Edition
Volume46
Issue number12
DOIs
StatePublished - 2007

Keywords

  • Electron microscopy
  • Fluorescence
  • Peptides
  • Self-assembly
  • Vesicles

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