Bimanes. 25. The Synthesis and Structures of Tricyclic Bimanes (μ-(Cn)-syn-(CH2,CH3 or C1)B)

Daniele Marciano, Michel Baud'huin, Baruch Zinger, Israel Goldberg, Edward M. Kosower*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

An effective synthesis of tricyclic bimanes (μ(Cn-syn-CM2,R1)B, R1 = CH3 or Cl)) (3a-g, = 1,2,3) from bis-acid chlorides via bis-3-keto esters and bis-pyrazolinones is described. The success of the synthesis is strong support for the previously proposed mechanism of bimane formation, via a diazacyclopentadienone and a diazoketene. Crystal structures for three chloro derivatives (3b-d, =1,2,3) reveal that the bimane dihedral ring angle and crystal packing details vary with the size of the third ring. Other spectroscopic properties (IR, UV, and NMR) vary with dihedral angle.

Original languageEnglish
Pages (from-to)7320-7328
Number of pages9
JournalJournal of the American Chemical Society
Volume112
Issue number20
DOIs
StatePublished - 1 Dec 1990

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