Bilateral retinal vasculitis associated with clotting disorders

H. Savir*, T. Wender, D. Creter, M. Djaldetti, R. Stein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We found distinct alterations of the clotting and fibrinolytic mechanisms in a 27-year-old man who suffered from typical bilateral retinal vasculitis, clinically and fluoroangiographically manifest as obstruction of the central retinal veins. The partial thromboplastin time was slightly increased, a partial clot lysis occurred after one hour, the plasminogen level was markedly low, and alpha2-macroglobulin was decreased, as were factor XII and IgG. Kallikrein was absent. Similar changes, though not so pronounced, were also found in the patient's son and in his brother.

Original languageEnglish
Pages (from-to)542-547
Number of pages6
JournalAmerican Journal of Ophthalmology
Issue number4
StatePublished - Oct 1977


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