TY - JOUR
T1 - Benign nasopharyngeal lymphoid tumors, lymphoepithelial lesions, and lymphocytic interstitial pneumonitis
AU - Puterman, Marco
AU - Fliss, Dan M.
AU - Coldstein, Jed
AU - Zirkin, Howard
PY - 1988/9
Y1 - 1988/9
N2 - A clinico‐pathologic and immunologic case study of a 57‐year‐old woman who has shown progressive lymphoid proliferations and lymphocyte dysfunction over the course of 10 years is presented. Early in the course ofher disease, she presented with recurrent benign nasopharyngeal lymphoid tumors. She subsequently developedbenign lymphoepithelial lesions involving both a submandibular and then a parotid salivary gland. She eventually underwent pneumonectomy for lymphocytic interstitial pneumonitis with marked cystic degeneration and lung destruction. Although frank malignancy has not been demonstrated review of her nasopharyngeal biopsies andof her pulmonary pathology shows a tendency toward distinct cellular uniformity with loss of follicles and germinal centers. Concurrently, immunologic studies have demonstrated abnormalities of cell mediated (T cell)function.
AB - A clinico‐pathologic and immunologic case study of a 57‐year‐old woman who has shown progressive lymphoid proliferations and lymphocyte dysfunction over the course of 10 years is presented. Early in the course ofher disease, she presented with recurrent benign nasopharyngeal lymphoid tumors. She subsequently developedbenign lymphoepithelial lesions involving both a submandibular and then a parotid salivary gland. She eventually underwent pneumonectomy for lymphocytic interstitial pneumonitis with marked cystic degeneration and lung destruction. Although frank malignancy has not been demonstrated review of her nasopharyngeal biopsies andof her pulmonary pathology shows a tendency toward distinct cellular uniformity with loss of follicles and germinal centers. Concurrently, immunologic studies have demonstrated abnormalities of cell mediated (T cell)function.
KW - benign lymphoepithelial lesions
KW - lymphocytic interstitial pneumonitis
KW - recurrent benign nasopharyngeal tumors
UR - http://www.scopus.com/inward/record.url?scp=0023696169&partnerID=8YFLogxK
U2 - 10.1002/jso.2930390108
DO - 10.1002/jso.2930390108
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C2 - 3419169
AN - SCOPUS:0023696169
SN - 0022-4790
VL - 39
SP - 35
EP - 38
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 1
ER -