Beneficial effect of granulocyte-colony stimulating factor in scleromyxoedema associated with severe idiopathic neutropenia

A. M. Cohen, E. Hodak, M. David, M. Mittelman, R. Gal, R. Stern

Research output: Contribution to journalArticlepeer-review

Abstract

The treatment of scleromyxoedema is notoriously difficult. We present a patient with long-standing diffuse scleromyxoedema associated with functional impairment who developed chronic idiopathic neutropenia complicated by recurrent life-threatening infections. Treatment with recombinant granulocyte-colony stimulating factor led to normalization of the neutrophil count, prevented further systemic infections, and unexpectedly was associated with a striking clinical improvement of her skin disorder and decrease in mucin deposition in the dermis.

Original languageEnglish
Pages (from-to)626-629
Number of pages4
JournalBritish Journal of Dermatology
Volume135
Issue number4
DOIs
StatePublished - 1996

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