TY - JOUR
T1 - Beneficial effect of granulocyte-colony stimulating factor in scleromyxoedema associated with severe idiopathic neutropenia
AU - Cohen, A. M.
AU - Hodak, E.
AU - David, M.
AU - Mittelman, M.
AU - Gal, R.
AU - Stern, R.
PY - 1996
Y1 - 1996
N2 - The treatment of scleromyxoedema is notoriously difficult. We present a patient with long-standing diffuse scleromyxoedema associated with functional impairment who developed chronic idiopathic neutropenia complicated by recurrent life-threatening infections. Treatment with recombinant granulocyte-colony stimulating factor led to normalization of the neutrophil count, prevented further systemic infections, and unexpectedly was associated with a striking clinical improvement of her skin disorder and decrease in mucin deposition in the dermis.
AB - The treatment of scleromyxoedema is notoriously difficult. We present a patient with long-standing diffuse scleromyxoedema associated with functional impairment who developed chronic idiopathic neutropenia complicated by recurrent life-threatening infections. Treatment with recombinant granulocyte-colony stimulating factor led to normalization of the neutrophil count, prevented further systemic infections, and unexpectedly was associated with a striking clinical improvement of her skin disorder and decrease in mucin deposition in the dermis.
UR - http://www.scopus.com/inward/record.url?scp=0029824257&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2133.1996.tb03846.x
DO - 10.1111/j.1365-2133.1996.tb03846.x
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AN - SCOPUS:0029824257
SN - 0007-0963
VL - 135
SP - 626
EP - 629
JO - British Journal of Dermatology
JF - British Journal of Dermatology
IS - 4
ER -