BCG and Autoimmunity

Emir Dogan, Omer Faruk Deniz, Omer Faruk Dogru, Naim Mahroum

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The nonspecific effects of BCG are not fully understood nevertheless, “trained immunity” and “heterologous lymphocyte responses” have been suggested. For instance, intravesical BCG therapy used for the treatment of bladder cancer, commonly causes minor side effects following treatment. On the other hand, severe complications, varying from isolated organ involvement to multisystem BCG disease, may occur less frequently but require specific treatment, and in some cases necessitate discontinuation of BCG therapy.

Original languageEnglish
Title of host publicationInfection and Autoimmunity
PublisherElsevier
Pages543-558
Number of pages16
ISBN (Electronic)9780323991308
ISBN (Print)9780323991315
DOIs
StatePublished - 1 Jan 2024
Externally publishedYes

Keywords

  • BCG
  • BCG and autoimmunity
  • Bacille Calmette-Guerin
  • Tuberculosis

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