Basal cell carcinomas arising over arteriovenous malformations: Some speculations on the theme

Meora Feinmesser*, Eytan Taube, Emanuel Badani, Don Kristt

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The modulating effects of mesoderm on ectoderm during the embryonic period have been well documented. Some cutaneous conditions such as dermatofibroma with basaloid proliferation are examples of such a relationship. Seven cases of basal cell carcinoma (BCC) developing in port- wine stains and one case developing over an arteriovenous (AV) malformation have been reported. We report 3 elderly patients with BCC developing over AV malformations of the lower extremities. The association between BCC and AV malformation range from a chance association to a complex interaction between mesenchyme and epithelium, in which mesenchyme induces and modulates epithelial growth through the elaboration of specific growth factors (GF).

Original languageEnglish
Pages (from-to)575-579
Number of pages5
JournalAmerican Journal of Dermatopathology
Volume19
Issue number6
DOIs
StatePublished - 1997

Keywords

  • Arteriovenous malformation
  • Basal cell carcinoma

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