Bartonella quintana, an unrecognized cause of infective endocarditis in children in Ethiopia

Diana Tasher, Alona Raucher-Sternfeld, Akiva Tamir, Michael Giladi, Eli Somekh

Research output: Contribution to journalArticlepeer-review

Abstract

Bartonella quintana endocarditis, a common cause of culture-negative endocarditis in adults, has rarely been reported in children. We describe 5 patients 7–16 years of age from Ethiopia with heart defects and endocarditis; 4 cases were caused by infection with B. quintana and 1 by Bartonella of undetermined species. All 5 patients were afebrile and oligosymptomatic, although 3 had heart failure. C-reactive protein was normal or slightly elevated, and erythrocyte sedimentation rate was high. The diagnosis was confirmed by echocardiographic demonstration of vegetations, the presence of high Bartonella IgG titers, and identification of B. quintana DNA in excised vegetations. Embolic events were diagnosed in 2 patients. Our data suggest that B. quintana is not an uncommon cause of native valve endocarditis in children in Ethiopia with heart defects and that possible B. quintana infection should be suspected and pursued among residents of and immigrants from East Africa, including Ethiopia, with culture-negative endocarditis.

Original languageEnglish
Pages (from-to)1246-1252
Number of pages7
JournalEmerging Infectious Diseases
Volume23
Issue number8
DOIs
StatePublished - Aug 2017

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