TY - JOUR
T1 - Balance testing with inertial sensors in patients with parkinson's disease
T2 - Assessment of motor subtypes
AU - Rocchi, Laura
AU - Palmerini, Luca
AU - Weiss, Aner
AU - Herman, Talia
AU - Hausdorff, Jeffrey M.
N1 - Publisher Copyright:
© 2013 IEEE.
PY - 2014/9/1
Y1 - 2014/9/1
N2 - In this study, the use of an instrumented balance test based on inertial sensors was evaluated in patients with Parkinson's disease (PD). We aimed to objectively characterize motor subtypes of PD [tremor dominant (TD) and postural instability gait difficulty (PIGD)], to help to quantitatively classify the PD subjects into motor subtypes. Subjects were studied performing postural tests, while wearing a device including a tri-axial accelerometer on the lower back, in four different experimental conditions that depended on feet position (feet-together or semi-tandem) and vision (eyes open or closed). Postural measures, after a reliability check, were tested to identify their sensitivity to the disease, to the PD subtypes, and to the experimental conditions. The results highlight the possibility of distinguishing between the TD and PIGD subtypes by means of objective postural measures that are able to detect tremor and PIGD features and are able to classify a subject as TD or PIGD with good accuracy. Feet position influences frequency measures, whereas eyes closure influences the displacement measures and enhances differences between PD and control subjects, suggesting that postural displacement measures may be capable of detecting different adaptation processes to external sensory conditions between patients with PD and control subjects.
AB - In this study, the use of an instrumented balance test based on inertial sensors was evaluated in patients with Parkinson's disease (PD). We aimed to objectively characterize motor subtypes of PD [tremor dominant (TD) and postural instability gait difficulty (PIGD)], to help to quantitatively classify the PD subjects into motor subtypes. Subjects were studied performing postural tests, while wearing a device including a tri-axial accelerometer on the lower back, in four different experimental conditions that depended on feet position (feet-together or semi-tandem) and vision (eyes open or closed). Postural measures, after a reliability check, were tested to identify their sensitivity to the disease, to the PD subtypes, and to the experimental conditions. The results highlight the possibility of distinguishing between the TD and PIGD subtypes by means of objective postural measures that are able to detect tremor and PIGD features and are able to classify a subject as TD or PIGD with good accuracy. Feet position influences frequency measures, whereas eyes closure influences the displacement measures and enhances differences between PD and control subjects, suggesting that postural displacement measures may be capable of detecting different adaptation processes to external sensory conditions between patients with PD and control subjects.
KW - Discriminative analysis
KW - Inertial sensors
KW - Parkinson's disease (PD)
KW - Postural instability gait difficulty (PIGD)
KW - Posture
KW - Tremor dominant (TD)
UR - http://www.scopus.com/inward/record.url?scp=84923344518&partnerID=8YFLogxK
U2 - 10.1109/TNSRE.2013.2292496
DO - 10.1109/TNSRE.2013.2292496
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C2 - 24760912
AN - SCOPUS:84923344518
SN - 1534-4320
VL - 22
SP - 1064
EP - 1071
JO - IEEE Transactions on Neural Systems and Rehabilitation Engineering
JF - IEEE Transactions on Neural Systems and Rehabilitation Engineering
IS - 5
M1 - 6678667
ER -