Abstract
Following the recent development of the one-pot two-step oxidation protocol for primary β-alkoxy alcohols, additional primary β-oxy alcohols were examined under similar conditions. The outcome of these reactions closely follows the migratory aptitudes of the related α-oxy-alkyls in Baeyer-Villiger oxidation vs. that of hydrogen. Thus, these experiments helped to establish the correct order of these aptitudes for α-oxy-alkyls. Furthermore, in the case of primary β,β-dialkoxyalcohols, the formation of dialkoxymethyl formates by the domino oxidation reaction was followed by secondary reactions, forming a number of interesting products.
Original language | English |
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Article number | 1275 |
Pages (from-to) | 1-13 |
Number of pages | 13 |
Journal | Catalysts |
Volume | 10 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2020 |
Keywords
- Domino reactions
- Migratory aptitudes
- Organocatalysis
- Oxidations
- Synthetic methods