Backward bifurcation in epidemic models: Problems arising with aggregated bifurcation parameters

Isaac Mwangi Wangari, Stephen Davis, Lewi Stone

Research output: Contribution to journalArticlepeer-review

Abstract

This study addresses problems that have arisen in the literature when calculating backward bifurcations, especially in the context of epidemic modeling. Backward bifurcations are generally studied by varying a bifurcation parameter which in epidemiological models is usually the so-called basic reproduction number R0. However, it is often overlooked that R0 is an aggregate of parameters in the model. One cannot simply vary the aggregate R0 while leaving all model parameters constant as has happened many times in the literature. We investigate two scenarios. For the incorrect approach we fix all parameters in the aggregate R0 to constant values, but R0 is nevertheless varied as a bifurcation parameter. In the correct approach, a key parameter in R0 is allowed to vary, and hence R0 itself varies and acts as a natural bifurcation parameter. We explore how the outcomes of these two approaches are substantially different.

Original languageEnglish
Pages (from-to)1669-1675
Number of pages7
JournalApplied Mathematical Modelling
Volume40
Issue number2
DOIs
StatePublished - 15 Jan 2016

Keywords

  • Backward bifurcation
  • Backward bifurcation threshold R
  • Basic reproduction number
  • Epidemic models

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