TY - JOUR
T1 - Axial growth of the fetal eye and evaluation of the hyaloid artery
T2 - In utero ultrasonographic study
AU - Achiron, Reuwen
AU - Kreiser, Doron
AU - Achiron, Anat
PY - 2000
Y1 - 2000
N2 - The aims of this prospective, cross-sectional study were to report axial ocular growth during human gestation, to determine the presence of the hyaloid artery (HA) and its blood flow, and to provide a timetable for HA regression. The study group comprised 231 low-risk singleton pregnancies between 14 and 38 weeks' gestation. Ocular axial length (OAL), anterior chamber depth (ACD) and posterior chamber depth (PCD) were measured using high-resolution ultrasound. The growth of these eye segments in correlation with gestational age (GA) was established. The presence of the HA and its regression were determined. By using power Doppler, ultrasound blood flow within the HA was estimated. HA regression is a gradual process that is not evident before 18 weeks' gestation. In all fetuses beyond 29 weeks' gestation, no HA could be detected (P < 0.001). Blood flow within the HA was documented only until the 16th week of gestation. The correlation coefficients, r = 0.924, 0.784 and 0.929, for OAL, ACD and PCD, respectively, were found to be highly statistically significant (P < 0.0001). The present data offer normative measurements of the fetal axial eye lengths, timetable for HA regression and flow cessation. Copyright (C) 2000 John Wiley and Sons, Ltd.
AB - The aims of this prospective, cross-sectional study were to report axial ocular growth during human gestation, to determine the presence of the hyaloid artery (HA) and its blood flow, and to provide a timetable for HA regression. The study group comprised 231 low-risk singleton pregnancies between 14 and 38 weeks' gestation. Ocular axial length (OAL), anterior chamber depth (ACD) and posterior chamber depth (PCD) were measured using high-resolution ultrasound. The growth of these eye segments in correlation with gestational age (GA) was established. The presence of the HA and its regression were determined. By using power Doppler, ultrasound blood flow within the HA was estimated. HA regression is a gradual process that is not evident before 18 weeks' gestation. In all fetuses beyond 29 weeks' gestation, no HA could be detected (P < 0.001). Blood flow within the HA was documented only until the 16th week of gestation. The correlation coefficients, r = 0.924, 0.784 and 0.929, for OAL, ACD and PCD, respectively, were found to be highly statistically significant (P < 0.0001). The present data offer normative measurements of the fetal axial eye lengths, timetable for HA regression and flow cessation. Copyright (C) 2000 John Wiley and Sons, Ltd.
KW - Eye
KW - Fetus
KW - Ligaloid artery
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=0033659138&partnerID=8YFLogxK
U2 - 10.1002/1097-0223(200011)20:11<894::AID-PD949>3.0.CO;2-J
DO - 10.1002/1097-0223(200011)20:11<894::AID-PD949>3.0.CO;2-J
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AN - SCOPUS:0033659138
SN - 0197-3851
VL - 20
SP - 894
EP - 899
JO - Prenatal Diagnosis
JF - Prenatal Diagnosis
IS - 11
ER -