Autologous bone marrow transplantation in pediatric solid tumors

Isaac Yaniv*, Eric Bouffet, Claude Irle, Sylvie Negrier, Pierre Biron, Marie Favrot, Irène Philip, Maud Brunat-Mentigny, Thierry Philip

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

During the last 5 years massive chemotherapy and autologous bone marrow transplantation have been increasingly explored in the treatment of pediatric solid tumors, mainly for neuroblastoma, Ewing's sarcoma, rhabdomyosarcoma, Wilms' tumor, germ cell tumors, osteosarcoma, and retinoblastoma. Although the disease course could be changed successfully in most instances, the long-term survival has not yet been improved much over the best available conventional treatments. Despite this, in responding relapsed patients this approach seems promising and may represent the only chance of cure. New and better induction regimens are needed.

Original languageEnglish
Pages (from-to)35-46
Number of pages12
JournalPediatric Hematology and Oncology
Volume7
Issue number1
DOIs
StatePublished - 1990
Externally publishedYes

Funding

FundersFunder number
Association pour la Recherche sur le Cancer6243
Institut national de la santé et de la recherche médicale48.60.22
Ligue Contre le Cancer

    Keywords

    • Autologous bone marrow transplantation
    • Dose effect
    • Pediatric oncology

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