TY - JOUR
T1 - Autoinductive exponential signal amplification
T2 - A diagnostic probe for direct detection of fluoride
AU - Perry-Feigenbaum, Rotem
AU - Sella, Eran
AU - Shabat, Doron
PY - 2011/10/17
Y1 - 2011/10/17
N2 - A new example of an exponential signal amplification strategy for the direct detection of fluoride is demonstrated. The amplification occurred through reaction of fluoride with a responsive chromogenic probe. The probe activity is based on a unique dendritic chain reaction that generates a fluoride anion, which is the analyte of interest, during the disassembly pathway of the dendritic probe. This autoinductive amplification mechanism may be applied for detection of other analytes by coupling activity of a modified probe with that of the fluoride amplifier.
AB - A new example of an exponential signal amplification strategy for the direct detection of fluoride is demonstrated. The amplification occurred through reaction of fluoride with a responsive chromogenic probe. The probe activity is based on a unique dendritic chain reaction that generates a fluoride anion, which is the analyte of interest, during the disassembly pathway of the dendritic probe. This autoinductive amplification mechanism may be applied for detection of other analytes by coupling activity of a modified probe with that of the fluoride amplifier.
KW - analytes
KW - dendrimers
KW - dyes/pigments
KW - fluoride
KW - reaction mechanisms
UR - http://www.scopus.com/inward/record.url?scp=80054019415&partnerID=8YFLogxK
U2 - 10.1002/chem.201101796
DO - 10.1002/chem.201101796
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AN - SCOPUS:80054019415
SN - 0947-6539
VL - 17
SP - 12123
EP - 12128
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
IS - 43
ER -