Autoinductive exponential signal amplification: A diagnostic probe for direct detection of fluoride

Rotem Perry-Feigenbaum, Eran Sella, Doron Shabat*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A new example of an exponential signal amplification strategy for the direct detection of fluoride is demonstrated. The amplification occurred through reaction of fluoride with a responsive chromogenic probe. The probe activity is based on a unique dendritic chain reaction that generates a fluoride anion, which is the analyte of interest, during the disassembly pathway of the dendritic probe. This autoinductive amplification mechanism may be applied for detection of other analytes by coupling activity of a modified probe with that of the fluoride amplifier.

Original languageEnglish
Pages (from-to)12123-12128
Number of pages6
JournalChemistry - A European Journal
Volume17
Issue number43
DOIs
StatePublished - 17 Oct 2011

Keywords

  • analytes
  • dendrimers
  • dyes/pigments
  • fluoride
  • reaction mechanisms

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