Autoimmune polyglandular failure associated with malabsorption and gastric carcinoid tumour

G. LEIBOWITZ*, G. AMIR, I. S. LOSSES, R. ELIAKIM

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Abstract. A 21‐year‐old female with autoimmune polyglandular failure (APG) manifested by insulin‐dependent diabetes mellitus (IDDM), hypothyroidism and pernicious anaemia developed severe malabsorption due to exocrine pancreatic insufficiency. Supplemental pancreatic enzymes resulted in marked improvement of steatorrhea. There was also an incidental finding of gastric carcinoid tumour. We identified only 13 other patients in our institution with either type 2 or 3 APG, one of which had significant steatorrhoea. Another patient with IDDM, hypothyroidism and pernicious anaemia had an asymptomatic gastric carcinoid tumour. The possible mechanisms for malabsorption in APG are discussed. 1993 Blackwell Publishing Ltd

Original languageEnglish
Pages (from-to)625-629
Number of pages5
JournalJournal of Internal Medicine
Volume234
Issue number6
DOIs
StatePublished - Dec 1993
Externally publishedYes

Keywords

  • autoimmune polyglandular failure
  • carcinoid
  • malabsorption

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