Autoantibody spread may explain multiple antibodies

J. George, B. Gilburd, Y. Shoenfeld

Research output: Contribution to journalArticlepeer-review

Abstract

In this paper by Jacob George, Boris Gilburd, and Yehuda Shoenfeld, the presence of multiple autoantibodies in many autoimmune conditions is discussed. The authors propose an autoantibody spreading concept to account for this, based on animal models in which immunization with a given antibody causes an antibody response towards associated molecules as well as to apparently nonrelated antigens.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalImmunologist
Volume7
Issue number6
StatePublished - 1999

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