Auto-inflammatory Fever Syndromes

Shai Padeh, Yakov Berkun

Research output: Contribution to journalReview articlepeer-review


The term autoinflammatory disease has been proposed to describe a group of disorders characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells. The last decade has witnessed tremendous advances in the understanding of these disorders. These advances have allowed therapeutic interventions, resulting in improvement in the short-term and long-term morbidity of all of these diseases. Future research into the molecular mechanisms underlying these inflammatory diseases should lead to a better understanding of inflammatory diseases in general and, it is hoped, to better and more targeted therapies.

Original languageEnglish
Pages (from-to)585-623
Number of pages39
JournalRheumatic Disease Clinics of North America
Issue number3
StatePublished - Aug 2007


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