Augmentation of bupivacaine analgesia in labor by epidural morphine

David Niv, Valery Rudick, Abraham Golan, Mark S. Chayen

Research output: Contribution to journalArticlepeer-review


The analgesic properties and motor effect of epidural 0.257c bupivacaine (8 mL) were compared with those of epidural morphine (2 mg in 10 mL saline) followed by 8 mL of 0.25% bupivacaine. The study was performed on two groups of parturients (30 in each group) in active labor. Pain relief in the morphine-bupivacaine group lasted for a mean of 131.1 minutes (SD ± 49.8) as opposed to the plain bupivacaine group -57 minutes (SD ± 15.28). Satisfaction from analgesia in the morphine-bupivacaine group was higher as well. Motor involvement was not seen in either group. Perineal pain relief in the postpartum period lasted for a mean of 16 hours and 40 minutes in the morphine-bupivacaine group. It was concluded that the concomitant use of epidural morphine augmented the analgesic effect of 0.25% bupivacaine without motor effect.

Original languageEnglish
Pages (from-to)206-209
Number of pages4
JournalObstetrics and Gynecology
Issue number2
StatePublished - Feb 1986


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