Atypical cutaneous findings in a patient with systemic lupus erythematosus

O. Elkayam, A. Gat, M. Lidgi, R. Segal, M. Yaron, D. Caspi

Research output: Contribution to journalArticlepeer-review

Abstract

A previously diagnosed systemic lupus erythematosus patient presented with arthralgia, skin rash and muscular weakness. When treated with high-dose corticosteroids and methotrexate she improved, except for a persistent lesion in the hand which evolved into a profound ulcer, along with tender subcutaneous nodules in the calf. A skin biopsy disclosed necrotizing vasculitis with giant cell granuloma revealing acid fast positive bacteria on ziels nilsen staining. A chest X-ray disclosed miliary tuberculosis (TB). The patient was diagnosed as miliary TB with prominent cutaneous involvement and treated with four anti-tuberculous drugs with slow resolution of her systemic, pulmonary and skin signs.

Original languageEnglish
Pages (from-to)413-417
Number of pages5
JournalLupus
Volume12
Issue number5
DOIs
StatePublished - 2003
Externally publishedYes

Keywords

  • Cutaneous
  • Miliary
  • Systemic lupus erythematosus
  • Tuberculosis

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