TY - JOUR
T1 - Atrial fibrillation predicts cognitive impairment in patients with ischemic stroke
AU - Mizrahi, Eliyahu Hayim
AU - Waitzman, Anna
AU - Arad, Marina
AU - Adunsky, Abraham
PY - 2011/12
Y1 - 2011/12
N2 - Background: Atrial fibrillation (AF) is considered as a risk factor for cognitive impairment. Methods: This retrospective chart review study was conducted in a patient stroke rehabilitation ward of a university-affiliated referral hospital. The participants were 707 patients admitted for a standard rehabilitation course after an ischemic stroke. Cognitive status was assessed by the Mini-Mental State Examination (MMSE), and scores lower than 24 points were considered as suggestive of cognitive impairment. Results: Atrial fibrillation, age, gender, diabetes, and dementia emerged as the only statistically significant parameters differing between those with MMSE score lower than 24 or higher. In a multiple logistic regression analysis, AF (odds ratio 1.6, 95% confidence interval 1.03-2.47, P =.03) was associated with an increased risk of cognitive impairment. Conclusions:Our findings suggest that atrial fibrillation upon admission is independently associated with lower MMSE scores in patients with ischemic stroke.
AB - Background: Atrial fibrillation (AF) is considered as a risk factor for cognitive impairment. Methods: This retrospective chart review study was conducted in a patient stroke rehabilitation ward of a university-affiliated referral hospital. The participants were 707 patients admitted for a standard rehabilitation course after an ischemic stroke. Cognitive status was assessed by the Mini-Mental State Examination (MMSE), and scores lower than 24 points were considered as suggestive of cognitive impairment. Results: Atrial fibrillation, age, gender, diabetes, and dementia emerged as the only statistically significant parameters differing between those with MMSE score lower than 24 or higher. In a multiple logistic regression analysis, AF (odds ratio 1.6, 95% confidence interval 1.03-2.47, P =.03) was associated with an increased risk of cognitive impairment. Conclusions:Our findings suggest that atrial fibrillation upon admission is independently associated with lower MMSE scores in patients with ischemic stroke.
KW - atrial fibrillation
KW - cognitive impairment
KW - ischemic stroke
KW - vascular risk factors.
UR - http://www.scopus.com/inward/record.url?scp=84857344141&partnerID=8YFLogxK
U2 - 10.1177/1533317511432733
DO - 10.1177/1533317511432733
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AN - SCOPUS:84857344141
SN - 1533-3175
VL - 26
SP - 623
EP - 626
JO - American Journal of Alzheimer's Disease and other Dementias
JF - American Journal of Alzheimer's Disease and other Dementias
IS - 8
ER -
