TY - JOUR
T1 - Atomic insight into short helical peptide comprised of consecutive multiple aromatic residues
AU - Misra, Rajkumar
AU - Vijayakanth, Thangavel
AU - Shimon, Linda J.W.
AU - Adler-Abramovich, Lihi
N1 - Publisher Copyright:
© 2022 The Royal Society of Chemistry
PY - 2022/5/12
Y1 - 2022/5/12
N2 - The occurrence of sequential multiple aromatic residues in a helical sequence is rare compared to the β-sheet rich structure. Here, using helix promoting α-aminoisobutyric acid (Aib) residues, we unravel atomistic details of the helical secondary structure formation and the super helical assembly of two heptapeptides composed of sequential five and six phenylalanine (Phe) residues.
AB - The occurrence of sequential multiple aromatic residues in a helical sequence is rare compared to the β-sheet rich structure. Here, using helix promoting α-aminoisobutyric acid (Aib) residues, we unravel atomistic details of the helical secondary structure formation and the super helical assembly of two heptapeptides composed of sequential five and six phenylalanine (Phe) residues.
UR - http://www.scopus.com/inward/record.url?scp=85131215806&partnerID=8YFLogxK
U2 - 10.1039/d2cc01038k
DO - 10.1039/d2cc01038k
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C2 - 35548938
AN - SCOPUS:85131215806
SN - 1359-7345
VL - 58
SP - 6445
EP - 6448
JO - Chemical Communications
JF - Chemical Communications
IS - 44
ER -