Association of inflammatory markers with hearing loss in young adults

Udi Shapira*, Hadas Ben Assayag, Omer J. Ungar, Ophir Handzel, Rani Abu Eta, Ori Rogowski, David Zeltser, Shlomo Berliner, Shani Shenhar-Tsarfaty, Yahav Oron

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objectives: To assess the correlation between inflammatory markers (IM) and hearing loss (HL) in a large cohort of apparently healthy individuals. Design: A cross sectional study. Setting: Tel-Aviv Medical Center (a tertiary referral center) Inflammatory Survey Participants Individuals who attended the Tel-Aviv Medical Center Inflammatory Survey (TAMCIS) for a routine annual health check. Results: Out of 2,500 individuals included in the final study cohort, 1,170 (47.3%) had some hearing impairment. Those with a hearing loss in 1 or both ears had significantly higher levels of neutrophils, lymphocytes, neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, and red blood cell counts. There was a difference between low- and high- frequencies losses associated with the inflammatory status. Conclusions: IM levels were associated with the presence of a HL, supporting a link between inflammatory changes and hearing loss.

Original languageEnglish
Pages (from-to)220-225
Number of pages6
JournalClinical Otolaryngology
Issue number2
StatePublished - Mar 2023


  • hearing loss
  • inflammation
  • markers


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