Association of Gaucher's Disease and lymphoid malignancy in 2 children

Y. Burstein, G. Rechavi, A. R. Rausen, B. Frisch, Z. Spirer

Research output: Contribution to journalArticlepeer-review

Abstract

2 cases of acute lymphoblastic leukaemia (ALL) of childhood in association with Gaucher's Disease (GD) are presented, which are the first to be described. One of them is a common non‐B non‐T cell ALL and the other is at T‐cell ALL. The association of GD with benign and malignant B‐cell proliferation has recently been described. It is suggested that chronic stimulation of the immune system by the accumulated glucocerebroside may predispose to B cell proliferation.

Original languageEnglish
Pages (from-to)445-447
Number of pages3
JournalScandinavian Journal of Haematology
Volume35
Issue number4
DOIs
StatePublished - Oct 1985
Externally publishedYes

Keywords

  • Gaucher's Disease
  • childhood acute leukaemia

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