Association of Gaucher's Disease and lymphoid malignancy in 2 children

Y. Burstein; G. Rechavi; A. R. Rausen; B. Frisch; Z. Spirer

doi:10.1111/j.1600-0609.1985.tb02269.x

Association of Gaucher's Disease and lymphoid malignancy in 2 children

Y. Burstein, G. Rechavi, A. R. Rausen, B. Frisch, Z. Spirer^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

2 cases of acute lymphoblastic leukaemia (ALL) of childhood in association with Gaucher's Disease (GD) are presented, which are the first to be described. One of them is a common non‐B non‐T cell ALL and the other is at T‐cell ALL. The association of GD with benign and malignant B‐cell proliferation has recently been described. It is suggested that chronic stimulation of the immune system by the accumulated glucocerebroside may predispose to B cell proliferation.

Original language	English
Pages (from-to)	445-447
Number of pages	3
Journal	Scandinavian Journal of Haematology
Volume	35
Issue number	4
DOIs	https://doi.org/10.1111/j.1600-0609.1985.tb02269.x
State	Published - Oct 1985
Externally published	Yes

Keywords

Gaucher's Disease
childhood acute leukaemia

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10.1111/j.1600-0609.1985.tb02269.x

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title = "Association of Gaucher's Disease and lymphoid malignancy in 2 children",

abstract = "2 cases of acute lymphoblastic leukaemia (ALL) of childhood in association with Gaucher's Disease (GD) are presented, which are the first to be described. One of them is a common non‐B non‐T cell ALL and the other is at T‐cell ALL. The association of GD with benign and malignant B‐cell proliferation has recently been described. It is suggested that chronic stimulation of the immune system by the accumulated glucocerebroside may predispose to B cell proliferation.",

keywords = "Gaucher's Disease, childhood acute leukaemia",

author = "Y. Burstein and G. Rechavi and Rausen, {A. R.} and B. Frisch and Z. Spirer",

year = "1985",

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doi = "10.1111/j.1600-0609.1985.tb02269.x",

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volume = "35",

pages = "445--447",

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AU - Burstein, Y.

AU - Rechavi, G.

AU - Rausen, A. R.

AU - Frisch, B.

AU - Spirer, Z.

PY - 1985/10

Y1 - 1985/10

N2 - 2 cases of acute lymphoblastic leukaemia (ALL) of childhood in association with Gaucher's Disease (GD) are presented, which are the first to be described. One of them is a common non‐B non‐T cell ALL and the other is at T‐cell ALL. The association of GD with benign and malignant B‐cell proliferation has recently been described. It is suggested that chronic stimulation of the immune system by the accumulated glucocerebroside may predispose to B cell proliferation.

AB - 2 cases of acute lymphoblastic leukaemia (ALL) of childhood in association with Gaucher's Disease (GD) are presented, which are the first to be described. One of them is a common non‐B non‐T cell ALL and the other is at T‐cell ALL. The association of GD with benign and malignant B‐cell proliferation has recently been described. It is suggested that chronic stimulation of the immune system by the accumulated glucocerebroside may predispose to B cell proliferation.

KW - Gaucher's Disease

KW - childhood acute leukaemia

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JO - Scandinavian Journal of Haematology

JF - Scandinavian Journal of Haematology

IS - 4

ER -

Association of Gaucher's Disease and lymphoid malignancy in 2 children

Abstract

Keywords

UN SDGs

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