Assessment of neurolymphomatosis by brachial plexus biopsy and PET/CT. Report of a case

Felix Bokstein, Odelyia Goor, Boris Shihman, Shimon Rochkind, Einat Even-Sapir, Ur Metser, Miri Neufeld

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To report a biopsy-proven neurolymphomatosis in a young woman with previous non-Hodgkin's lymphoma (NHL) of uterine cervix. Patient: The patient presented with a painful brachial plexopathy and developed multiple cranial and spinal nerve palsies. Methods and results: The diagnosis was achieved by an open brachial plexus biopsy. A PET/CT study was used to assess the full extent of the disease and showed involvement of additional cranial nerves and spinal nerve roots. A complete although short lasting clinical and radiological response was achieved by means of systemic high dose methotrexate treatment combined with rituximab and intra-CSF injections of cytarabine.

Original languageEnglish
Pages (from-to)163-167
Number of pages5
JournalJournal of Neuro-Oncology
Volume72
Issue number2
DOIs
StatePublished - Apr 2005
Externally publishedYes

Keywords

  • FTG PET
  • Methotrexate
  • Nerve biopsy
  • Neurolymphomatosis
  • Non-Hodgkin's lymphoma

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