Assessment of Interstitial Fluid Pressure in solid tumors via image processing of DCE-MRI

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Interstitial Fluid Pressure (IFP) is a major obstacle to intra-tumoral drug delivery. A routine non-invasive assessment of IFP will serve as a valuable predictor for the response to neoadjuvant treatment in breast cancer. It will also be the basis for a rationalized and personalized therapy by improving the efficacy of anti-cancer therapeutics via reduction of tumor IFP. We developed an automated robust algorithm for assessing IFP based on image analysis of dynamic contrast-enhanced MRI (DCE-MRI) examinations. This method is easy to implement on any MRI dataset of breast cancer and does not require any input from the radiologist besides delineating the tumor region.

Original languageEnglish
Title of host publicationIST 2016 - 2016 IEEE International Conference on Imaging Systems and Techniques, Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages189-194
Number of pages6
ISBN (Electronic)9781509018178
DOIs
StatePublished - 7 Nov 2016
Event2016 IEEE International Conference on Imaging Systems and Techniques, IST 2016 - Chania, Crete Island, Greece
Duration: 4 Oct 20166 Oct 2016

Publication series

NameIST 2016 - 2016 IEEE International Conference on Imaging Systems and Techniques, Proceedings

Conference

Conference2016 IEEE International Conference on Imaging Systems and Techniques, IST 2016
Country/TerritoryGreece
CityChania, Crete Island
Period4/10/166/10/16

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