TY - JOUR
T1 - Asplenia and functional hyposplenism in autoimmune polyglandular syndrome type 1
AU - Pollak, Uri
AU - Bar-Sever, Zvi
AU - Hoffer, Vered
AU - Marcus, Nufar
AU - Scheuerman, Oded
AU - Garty, Ben Zion
PY - 2009/2
Y1 - 2009/2
N2 - Asplenia was diagnosed in four patients with autoimmune polyendocrine syndrome type-I (APS-I): two children, aged 2-4 years, from the same family and two adults, the father of the two children and his cousin. We have observed a worsening in splenic function in the children during a follow-up of a few years. Patients with APS-I should be evaluated for splenic function, since splenic dysfunction has important therapeutic implications, especially in children.
AB - Asplenia was diagnosed in four patients with autoimmune polyendocrine syndrome type-I (APS-I): two children, aged 2-4 years, from the same family and two adults, the father of the two children and his cousin. We have observed a worsening in splenic function in the children during a follow-up of a few years. Patients with APS-I should be evaluated for splenic function, since splenic dysfunction has important therapeutic implications, especially in children.
KW - Asplenia
KW - Autoimmune polyglandular syndrome
UR - http://www.scopus.com/inward/record.url?scp=58149086553&partnerID=8YFLogxK
U2 - 10.1007/s00431-008-0735-9
DO - 10.1007/s00431-008-0735-9
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C2 - 18496713
AN - SCOPUS:58149086553
SN - 0340-6199
VL - 168
SP - 233
EP - 235
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 2
ER -