Arboviruses and Viral Hemorrhagic Fevers (VHF)

Eyal Meltzer

Research output: Contribution to journalReview articlepeer-review


The viral hemorrhagic fever (VHF) syndrome is a potentially life-threatening infection typified by a combination of a capillary leak syndrome and bleeding diathesis. Most but not all agents causing VHF are arboviruses, with transmission to humans resulting from an arthropod bite. Agents of VHF affect humans on all continents. Population growth, urbanization, human activities, and even climate change all contribute to a continual flux in the epidemiology of many arboviruses. This review provides an overview of the epidemiology of arboviral infections and VHF, the main clinical syndromes, and their diagnosis and treatment.

Original languageEnglish
Pages (from-to)479-496
Number of pages18
JournalInfectious Disease Clinics of North America
Issue number2
StatePublished - Jun 2012


  • Alphavirus
  • Arbovirus
  • Arenavirus
  • Bunyavirus
  • Filovirus
  • Flavivirus
  • Viral hemorrhagic fever


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