Approach to the Controlled Synthesis of Nucleopeptides I. Nε‐(6‐Purinoyl‐L‐Lysine and β‐(5‐Uracilyl)‐Dl‐Alanine

A. Vincze, Ch Lachman, S. Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

Nε‐(6‐purinoyl)‐L‐lysine has been prepared by acylation of L‐lysine copper complex or Nα‐carbobenzoxy‐L‐lysine with 6‐trichloromethylpurine followed by the removal of the protecting group. β‐(5‐uracilyl)‐DL‐alanine has been prepared by condensation of 5‐chloro‐methyluracil with diethyl acetamidomalonate, followed by acid hydrolysis.

Original languageEnglish
Pages (from-to)641-646
Number of pages6
JournalIsrael Journal of Chemistry
Volume6
Issue number5
DOIs
StatePublished - 1968
Externally publishedYes

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