Approach to the Controlled Synthesis of Nucleopeptides I. Nε‐(6‐Purinoyl‐L‐Lysine and β‐(5‐Uracilyl)‐Dl‐Alanine

A. Vincze; Ch Lachman; S. Cohen

doi:10.1002/ijch.196800081

Approach to the Controlled Synthesis of Nucleopeptides I. N^ε‐(6‐Purinoyl‐L‐Lysine and β‐(5‐Uracilyl)‐Dl‐Alanine

A. Vincze, Ch Lachman, S. Cohen

Research output: Contribution to journal › Article › peer-review

Abstract

N^ε‐(6‐purinoyl)‐L‐lysine has been prepared by acylation of L‐lysine copper complex or N^α‐carbobenzoxy‐L‐lysine with 6‐trichloromethylpurine followed by the removal of the protecting group. β‐(5‐uracilyl)‐DL‐alanine has been prepared by condensation of 5‐chloro‐methyluracil with diethyl acetamidomalonate, followed by acid hydrolysis.

Original language	English
Pages (from-to)	641-646
Number of pages	6
Journal	Israel Journal of Chemistry
Volume	6
Issue number	5
DOIs	https://doi.org/10.1002/ijch.196800081
State	Published - 1968
Externally published	Yes

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abstract = "Nε‐(6‐purinoyl)‐L‐lysine has been prepared by acylation of L‐lysine copper complex or Nα‐carbobenzoxy‐L‐lysine with 6‐trichloromethylpurine followed by the removal of the protecting group. β‐(5‐uracilyl)‐DL‐alanine has been prepared by condensation of 5‐chloro‐methyluracil with diethyl acetamidomalonate, followed by acid hydrolysis.",

author = "A. Vincze and Ch Lachman and S. Cohen",

year = "1968",

doi = "10.1002/ijch.196800081",

language = "אנגלית",

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journal = "Israel Journal of Chemistry",

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AU - Lachman, Ch

AU - Cohen, S.

PY - 1968

Y1 - 1968

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AB - Nε‐(6‐purinoyl)‐L‐lysine has been prepared by acylation of L‐lysine copper complex or Nα‐carbobenzoxy‐L‐lysine with 6‐trichloromethylpurine followed by the removal of the protecting group. β‐(5‐uracilyl)‐DL‐alanine has been prepared by condensation of 5‐chloro‐methyluracil with diethyl acetamidomalonate, followed by acid hydrolysis.

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Approach to the Controlled Synthesis of Nucleopeptides I. N^ε‐(6‐Purinoyl‐L‐Lysine and β‐(5‐Uracilyl)‐Dl‐Alanine

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