TY - JOUR
T1 - Application of comparative genomic hybridization technique for detection of chromosomal aberrations in benign cystic teratoma
AU - Amiel, A.
AU - Atzmon, H.
AU - Klein, Z.
AU - Kidron, D.
AU - Gaber, E.
AU - Vassilyev, O.
AU - Shalom-Paz, E.
AU - Fishman, A.
AU - Fejgin, M. D.
PY - 2003/7/1
Y1 - 2003/7/1
N2 - Benign cystic teratoma, also known as dermoid cyst, is the most common of all ovarian neoplasms accounting for 10%-20% of all ovarian cysts. Most have a normal 46,XX karyotype. Less than 2% can undergo malignant transformation. By using the comparative genomic hybridization technique on nine benign ovarian cysts we were able to show two cases with chromosomal aberrations not seen before in dermoid cysts but known to be involved in malignant ovarian tumors. We speculate that these are the tumors carrying the potential for malignant transformation.
AB - Benign cystic teratoma, also known as dermoid cyst, is the most common of all ovarian neoplasms accounting for 10%-20% of all ovarian cysts. Most have a normal 46,XX karyotype. Less than 2% can undergo malignant transformation. By using the comparative genomic hybridization technique on nine benign ovarian cysts we were able to show two cases with chromosomal aberrations not seen before in dermoid cysts but known to be involved in malignant ovarian tumors. We speculate that these are the tumors carrying the potential for malignant transformation.
UR - http://www.scopus.com/inward/record.url?scp=0038457086&partnerID=8YFLogxK
U2 - 10.1016/S0165-4608(02)00927-5
DO - 10.1016/S0165-4608(02)00927-5
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AN - SCOPUS:0038457086
SN - 0165-4608
VL - 144
SP - 73
EP - 75
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -
