[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].

Tamar Miller-Roll; Izabella Pilcha; Natan Weksler; Sorina Negomireanu; Murat Bahar

[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].

Tamar Miller-Roll^*, Izabella Pilcha, Natan Weksler, Sorina Negomireanu, Murat Bahar

^*Corresponding author for this work

Anesthesiology & Intensive Care

Assaf Harofeh Medical Center

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A 30 years old parturient was admitted to the operating theatre for revision of uterus after spontaneous labor because of hemorrhage. She underwent general anesthesia induced by rapid sequence induction (RSI) technique. Apnea for 45 minutes was observed after succinylcholine administration. Biochemistry laboratory tests from the operation day showed very low butyrylcholinesterase activity, and a repeated test after one month showed normal enzyme activity and inhibitors within the normal range. Genetic tests revealed heterozygosity for the K variant of BChE. This may explain the increased sensitivity to succinylcholine during pregnancy.

Original language	English
Pages (from-to)	402-404, 436
Journal	Harefuah
Volume	151
Issue number	7
State	Published - Jul 2012

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title = "[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].",

abstract = "A 30 years old parturient was admitted to the operating theatre for revision of uterus after spontaneous labor because of hemorrhage. She underwent general anesthesia induced by rapid sequence induction (RSI) technique. Apnea for 45 minutes was observed after succinylcholine administration. Biochemistry laboratory tests from the operation day showed very low butyrylcholinesterase activity, and a repeated test after one month showed normal enzyme activity and inhibitors within the normal range. Genetic tests revealed heterozygosity for the K variant of BChE. This may explain the increased sensitivity to succinylcholine during pregnancy.",

author = "Tamar Miller-Roll and Izabella Pilcha and Natan Weksler and Sorina Negomireanu and Murat Bahar",

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T1 - [Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].

AU - Miller-Roll, Tamar

AU - Pilcha, Izabella

AU - Weksler, Natan

AU - Negomireanu, Sorina

AU - Bahar, Murat

PY - 2012/7

Y1 - 2012/7

N2 - A 30 years old parturient was admitted to the operating theatre for revision of uterus after spontaneous labor because of hemorrhage. She underwent general anesthesia induced by rapid sequence induction (RSI) technique. Apnea for 45 minutes was observed after succinylcholine administration. Biochemistry laboratory tests from the operation day showed very low butyrylcholinesterase activity, and a repeated test after one month showed normal enzyme activity and inhibitors within the normal range. Genetic tests revealed heterozygosity for the K variant of BChE. This may explain the increased sensitivity to succinylcholine during pregnancy.

AB - A 30 years old parturient was admitted to the operating theatre for revision of uterus after spontaneous labor because of hemorrhage. She underwent general anesthesia induced by rapid sequence induction (RSI) technique. Apnea for 45 minutes was observed after succinylcholine administration. Biochemistry laboratory tests from the operation day showed very low butyrylcholinesterase activity, and a repeated test after one month showed normal enzyme activity and inhibitors within the normal range. Genetic tests revealed heterozygosity for the K variant of BChE. This may explain the increased sensitivity to succinylcholine during pregnancy.

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ER -

[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].

Abstract

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