Antitumor macrodiolides isolated from a marine sponge theonella sp. Structure revision of misakinolide A

Yuko Kato*, Nobuhiro Fusetani, Shiegeki Matsunaga, Kaneshisa Hashimoto, Ryuichi Sakai, Tatsuo Higa, Yoel Kashman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Two antitumor macrodiolides, bistheonellides A and B, were isolated from a marine sponge Theonella sp. Bistheonellide A was found to be identical with misakinolide A, whose structure has been revised from the previously proposed monomeric macrolide (3) to the dimeric macrodiolide (1). Similarly, bistheonellide B was deduced to be the related structure 2.

Original languageEnglish
Pages (from-to)6225-6228
Number of pages4
JournalTetrahedron Letters
Volume28
Issue number49
DOIs
StatePublished - 1987
Externally publishedYes

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