@article{98365b995254477db31685d0ce31f662,
title = "Anticodon nucleases",
abstract = "A tRNA(Lys)-specific anticodon nuclease is kept in a latent form in a rare Escherichia coli strain, complexed with a DNA restriction enzyme. A phage T4 inhibitor of DNA restriction activates anticodon nuclease, but other T4 proteins restore tRNA(Lys). Detection of a homologous system in Neisseria and a different anticodon nuclease in colicin E5 suggest ubiquity and diversity of such tRNA toxins. Analysis of these systems could reveal novel RNA recognition and cleavage mechanisms.",
author = "Gabriel Kaufmann",
note = "Funding Information: The author is indebted to Thomas Bickle, Hyouta Himeno, Larry Snyder and members of his laboratory for critical reading of the manuscript and useful suggestions. Relevant work in the author{\textquoteright}s laboratory is supported by grants from the Basic Science Foundation, the Israeli Academy of Sciences and Israeli Ministry of Health.",
year = "2000",
month = feb,
day = "1",
doi = "10.1016/S0968-0004(99)01525-X",
language = "אנגלית",
volume = "25",
pages = "70--74",
journal = "Trends in Biochemical Sciences",
issn = "0968-0004",
publisher = "Elsevier Ltd.",
number = "2",
}