Antibody molecules discriminate between crystalline facets of a gallium arsenide semiconductor

Arbel Artzy Schnirman, Efrat Zahavi, Hadas Yeger, Ronit Rosenfeld, Itai Benhar, Yoram Reiter, Uri Sivan

Research output: Contribution to journalArticlepeer-review

Abstract

Seamless integration of biomolecules with manmade materials will most likely rely on molecular recognition and specific binding. In the following we show that combinatorial antibody libraries, based on the vast repertoire of the human immune system, can be harnessed to generate such binders. As a demonstration, we isolate antibody fragments that discriminate and bind selectively GaAs (111A) facets as opposed to GaAs (100). The isolated antibodies are utilized for exclusive localization of a fluorescent dye on (111A) surfaces in a structure comprising a mixture of (100) and (111A) surfaces. The potential importance of structure rigidity to facet recognition is suggested vis-a-vis published experiments with short and longer peptides.

Original languageEnglish
Pages (from-to)1870-1874
Number of pages5
JournalNano Letters
Volume6
Issue number9
DOIs
StatePublished - Sep 2006

Fingerprint

Dive into the research topics of 'Antibody molecules discriminate between crystalline facets of a gallium arsenide semiconductor'. Together they form a unique fingerprint.

Cite this