Antibodies to brain antigens following stroke

N. M. Bornstein, B. Aronovich, A. D. Korczyn, S. Shavit, D. M. Michaelson, Joab Chapman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Cerebral necrosis following stroke exposes brain antigens to the immune system, potentially initiating an antibody response. The authors measured levels of antibodies to specific neuronal antigens, neurofilaments (NF), and a ubiquitous antigen, cardiolipin (CL), in 45 patients following an acute first-ever stroke, within 48 hours, and 1, 3, and 6 months later. The mean levels of anti-NF antibodies were elevated compared with baseline at 1, 3, and 6, months (p = 0.012, 0.002, and 0.003 by paired t-test). Anti-CL levels did not change significantly.

Original languageEnglish
Pages (from-to)529-530
Number of pages2
Issue number4
StatePublished - 27 Feb 2001


Dive into the research topics of 'Antibodies to brain antigens following stroke'. Together they form a unique fingerprint.

Cite this