Anti-neuronal antibodies similar to those found in Alzheimer's disease induce memory dysfunction in rats

J. Chapman, G. Alroy, Z. Weiss, M. Faigon, J. Feldon, D. M. Michaelson

Research output: Contribution to journalArticlepeer-review

Abstract

Although the etiology and pathogenesis of the cholinergic degeneration in Alzheimer's disease are not known, several reports implicate immunological mechanisms. Recently we have shown that sera of Alzheimer's disease patients contain antibodies which bind specifically to the heavy molecular weight neurofilament protein of Torpedo cholinergic neurons. In the present study we investigated the possibility.

Original languageEnglish
Pages (from-to)297-305
Number of pages9
JournalNeuroscience
Volume40
Issue number2
DOIs
StatePublished - 1991

Fingerprint

Dive into the research topics of 'Anti-neuronal antibodies similar to those found in Alzheimer's disease induce memory dysfunction in rats'. Together they form a unique fingerprint.

Cite this