Anthropomorphic cardiac phantom for dynamic SPECT

A. Krakovich*, U. Zaretsky, E. Gelbart, I. Moalem, A. Naimushin, E. Rozen, M. Scheinowitz, R. Goldkorn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background: As myocardial blood flow measurement (MBF) in SPECT systems became recently available, significant effort has been devoted to its validation. For that purpose, we have developed a cardiac phantom that is able to mimic physiological radiotracer variation in the left ventricle cavity and in the myocardium, while performing beating-like motion. The new phantom is integrated inside a standard anthropomorphic torso allowing a realistic tissue attenuation and gamma-ray scattering Methods and Results: A mechanical cardiac phantom was integrated in a commercially available anthropomorphic torso. Using a GE Discovery 530c SPECT, measurements were performed. It was found that gamma-ray attenuation effects are significant and limit the MBF measurements to global/three-vessel resolution. Dynamic SPECT experiments were performed to validate MBF accuracy and showed mean relative error of 14%. Finally, the effect of varying radiotracer dose on the accuracy of dynamic SPECT was studied Conclusions: A dynamic cardiac phantom has been developed and successfully integrated in a standard SPECT torso. A good agreement was found between SPECT-reported MBF values and the expected results.

Original languageEnglish
JournalJournal of Nuclear Cardiology
DOIs
StateAccepted/In press - 2022

Keywords

  • SPECT
  • instrumentation
  • myocardial blood flow

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