Anterior uveitis as presenting sign of myeloproliferative disease

An 83-year-old woman was admitted to the hospital with anterior uveitis in her left eye. Physical examination and laboratory studies revealed a myeloproliferative disorder. Anterior chamber tap showed acellular proteinaceous material negative for Philadelphia chromosome. Treatment with hydroxyurea was begun, but the patient did not return for follow-up. The patient died 10 months after diagnosis. Anterior uveitis with hypopyon may be an ocular manifestation of myeloproliferative disorder.