TY - JOUR
T1 - Anterior chamber infiltration of CAR T-cells
AU - Jacoby, Elad
AU - Zloto, Ofira
AU - Vishnevskia Dai, Vicktoria
N1 - Publisher Copyright:
© 2021 The Author(s)
PY - 2021/12
Y1 - 2021/12
N2 - A unique image of anterior chamber infiltration in a 2-year-infant with leukemia, treated with CD19 CAR T cells. Despite significant lymphopenia and resemblance of fungal infection initially, biopsy and cytologic analysis from anterior chamber fluid confirmed that this was CAR T-cell infiltration, likely targeting microscopic leukemia, unknown to us treating physicians. This is a unique case in 2 aspects: first, to state the high quality of CAR T-cell trafficking; and second – given the wide use of these cells currently, this image may help educate clinicians regarding this potential diagnosis.
AB - A unique image of anterior chamber infiltration in a 2-year-infant with leukemia, treated with CD19 CAR T cells. Despite significant lymphopenia and resemblance of fungal infection initially, biopsy and cytologic analysis from anterior chamber fluid confirmed that this was CAR T-cell infiltration, likely targeting microscopic leukemia, unknown to us treating physicians. This is a unique case in 2 aspects: first, to state the high quality of CAR T-cell trafficking; and second – given the wide use of these cells currently, this image may help educate clinicians regarding this potential diagnosis.
KW - CAR T cells
KW - Leukemia
UR - http://www.scopus.com/inward/record.url?scp=85122639226&partnerID=8YFLogxK
U2 - 10.1016/j.ajoc.2021.101223
DO - 10.1016/j.ajoc.2021.101223
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C2 - 34746512
AN - SCOPUS:85122639226
SN - 2451-9936
VL - 24
JO - American Journal of Ophthalmology Case Reports
JF - American Journal of Ophthalmology Case Reports
M1 - 101223
ER -
