Anhidrotic ectodermal dysplasia with spontaneous corneal perforation and keratoconus

Guy J.Ben Simon*, Aaron Grinbaum

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A patient with anhidrotic ectodermal dysplasia and severe dry eyes was admitted with spontaneous corneal perforation in his right eye. The corneal perforation was sealed with cyanoacrylate glue and bandage contact lens placement. Three weeks later, the patient underwent penetrating keratoplasty. On follow-up examination, he had corneal graft abscess that was treated successfully with topical antibiotics and corneal erosion that was treated with a bandage contact lens. Corneal topography performed as a routine examination showed inferior corneal steepening typical of keratoconus in the left eye. This accidental discovery of keratoconus in the patient's left eye may suggest a possible association between anhidrotic ectodermal dysplasia and keratoconus.

Original languageEnglish
Pages (from-to)495-498
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging
Issue number6
StatePublished - 2004
Externally publishedYes


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