Anaplastic carcinoma of the thyroid

T. Hadar*, C. Mor, J. Shvero, R. Levy, K. Segal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

80 Scopus citations

Abstract

A review of 48 cases of anaplastic cell carcinoma of the thyroid gland treated in the Department of E.N.T. of Beilinson Medical Center revealed more than 90% of the patients to be over 50 years of age. Twenty-five percent of the patients showed histologically areas of transition front differentiated carcinoma (either papillary or follicular) into anaplastic carcinoma. The patients were treated by surgery and/or irradiation and/or chemotherapy. Twenty-seven patients underwent subtotal or total thyroidectomy and 21 patients underwent biopsy or partial thyroidectomy. The survival rate was very poor two-year survival rate was 28%. Twenty-eight of the patients (58%) died within one year of diagnosis.

Original languageEnglish
Pages (from-to)511-516
Number of pages6
JournalEuropean Journal of Surgical Oncology
Volume19
Issue number6
StatePublished - 1993
Externally publishedYes

Keywords

  • Anaplastic carcinoma
  • Total thyroidectomy
  • Well-differentiated carcinoma

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