Anaphylaxis to cisplatin: Diagnosis and value of pretreatment in prevention of recurrent allergic reactions

A. Goldberg, M. M. Altaras, Y. A. Mekori, Y. Beyth, R. Confino-Cohen

Research output: Contribution to journalArticlepeer-review

Abstract

Two patients, who developed anaphylaxis to cisplatin, are described. This phenomenon was preceded by mild allergic symptoms, which were overlooked, in previous treatment courses. Intradermal skin tests were both sensitive and specific in the diagnosis of cisplatin allergy. Pretreatment with antihistamines and corticosteroids was ineffective in preventing recurrent anaphylaxis. Thus, a trial of desensitization is mandatory among those patients whose disease responds to the administration of this agent.

Original languageEnglish
Pages (from-to)271-272
Number of pages2
JournalAnnals of Allergy
Volume73
Issue number3
StatePublished - 1994
Externally publishedYes

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