TY - JOUR
T1 - Anaphylaxis to cisplatin
T2 - Diagnosis and value of pretreatment in prevention of recurrent allergic reactions
AU - Goldberg, A.
AU - Altaras, M. M.
AU - Mekori, Y. A.
AU - Beyth, Y.
AU - Confino-Cohen, R.
PY - 1994
Y1 - 1994
N2 - Two patients, who developed anaphylaxis to cisplatin, are described. This phenomenon was preceded by mild allergic symptoms, which were overlooked, in previous treatment courses. Intradermal skin tests were both sensitive and specific in the diagnosis of cisplatin allergy. Pretreatment with antihistamines and corticosteroids was ineffective in preventing recurrent anaphylaxis. Thus, a trial of desensitization is mandatory among those patients whose disease responds to the administration of this agent.
AB - Two patients, who developed anaphylaxis to cisplatin, are described. This phenomenon was preceded by mild allergic symptoms, which were overlooked, in previous treatment courses. Intradermal skin tests were both sensitive and specific in the diagnosis of cisplatin allergy. Pretreatment with antihistamines and corticosteroids was ineffective in preventing recurrent anaphylaxis. Thus, a trial of desensitization is mandatory among those patients whose disease responds to the administration of this agent.
UR - http://www.scopus.com/inward/record.url?scp=0028129924&partnerID=8YFLogxK
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AN - SCOPUS:0028129924
VL - 73
SP - 271
EP - 272
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
SN - 1081-1206
IS - 3
ER -