Analysis of the antigen specific helper T cell function and HLA‐DR of Israeli patients with rheumatoid arthritis (RA)

M. Tishler, C. Brautbar, S. Battat, M. Dayan, E. Mozes*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Forty‐three patients with rheumatoid arthritis (RA) were studied for their ability to respond to the synthetic polypeptide antigen (T,G)‐A‐L as measured by the production of a T cell helper factor by their antigen activated T cells. Sixteen patients (37%) responded to (T,G)‐A‐L by the production of an antigen specific helper T cell factor, a percentage not significantly different from healthy donors. The production of antigen specific T cell helper factors was affected, although not significantly, by immune modulating drugs and by the presence of rheumatoid factor in sera of patients. The high incidence of HLA‐DR 4 reported for RA patients was not observed in this group of RA patients.

Original languageEnglish
Pages (from-to)229-234
Number of pages6
JournalTissue Antigens
Volume30
Issue number5
DOIs
StatePublished - Nov 1987
Externally publishedYes

Fingerprint

Dive into the research topics of 'Analysis of the antigen specific helper T cell function and HLA‐DR of Israeli patients with rheumatoid arthritis (RA)'. Together they form a unique fingerprint.

Cite this